Riboapt DB is the comprehensive database of Ribozymes and Aptamer sequences.

Ribozymes are RNAs which have catalytic property and Aptamers are either RNA or DNA oligonucleotides which can bind tightly to the target molecules like nucleic acids, proteins, lipids and ligands like organic, inorganic molecules.

The comprehensive sequence information on aptamers and ribozymes that have been generated by in vitro selection methods are included in this RiboaptDB database. Such types of unnatural data generated by in vitro methods are not available in the publicly available ‘natural’ sequence databases such as GeneBank.

The amount of sequence data generated by in vitro selection experiments has been accumulating exponentially. There are 370 artificial ribozyme sequences and 3842 aptamer sequences in the total 4212 sequences from 423 citations in this RiboaptDB.

We included general search feature, and individual feature wise search, user submission form for new data through online and also local BLAST search.

This database, besides serving as a storehouse of sequences that may have diagnostic or therapeutic utility in medicine, provides valuable information for computational and theoretical biologists.

The RiboaptDB is extremely useful for garnering information about in vitro selection experiments as a whole and for better understanding the distribution of functional nucleic acids in sequence space.